Inverse Correlation between Promoter Strength and Excision Activity in Class 1 Integrons
نویسندگان
چکیده
منابع مشابه
Inverse Correlation between Promoter Strength and Excision Activity in Class 1 Integrons
Class 1 integrons are widespread genetic elements that allow bacteria to capture and express gene cassettes that are usually promoterless. These integrons play a major role in the dissemination of antibiotic resistance among Gram-negative bacteria. They typically consist of a gene (intI) encoding an integrase (that catalyzes the gene cassette movement by site-specific recombination), a recombin...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2010
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1000793